Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Curated Information Page
PubMed Id: 9030583 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Tingley WG, et al. (1997) Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies. J Biol Chem 272, 5157-66 9030583
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
Download Sites

S890-p - NMDAR1 (rat)
Orthologous residues
NMDAR1 (human): S890‑p, NMDAR1 iso2 (human): , NMDAR1 iso5 (human): S911‑p, NMDAR1 (mouse): S890‑p, NMDAR1 iso2 (mouse): , NMDAR1 iso3 (mouse): S911‑p, NMDAR1 (rat): S890‑p, NMDAR1 iso7 (rat):
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  'brain, hippocampus', 293 (epithelial), QT-6 (fibroblast)
 Cellular systems studied:  cell lines, tissue
 Species studied:  human, quail, rat
 Comments:  transfected 293 and QT-6 cells, and hippocampal slices
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKCA (rat)
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol ester increase
forskolin no change compared to control
Downstream Regulation
 Effect of modification (function):  intracellular localization

S896-p - NMDAR1 (rat)
Orthologous residues
NMDAR1 (human): S896‑p, NMDAR1 iso2 (human): , NMDAR1 iso5 (human): S917‑p, NMDAR1 (mouse): S896‑p, NMDAR1 iso2 (mouse): , NMDAR1 iso3 (mouse): S917‑p, NMDAR1 (rat): S896‑p, NMDAR1 iso7 (rat):
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  'brain, hippocampus', 293 (epithelial), QT-6 (fibroblast)
 Cellular systems studied:  cell lines, tissue
 Species studied:  human, quail, rat
 Comments:  transfected 293 and QT-6 cells, and hippocampal slices
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKCA (rat)

S897-p - NMDAR1 (rat)
Orthologous residues
NMDAR1 (human): S897‑p, NMDAR1 iso2 (human): , NMDAR1 iso5 (human): S918‑p, NMDAR1 (mouse): S897‑p, NMDAR1 iso2 (mouse): , NMDAR1 iso3 (mouse): S918‑p, NMDAR1 (rat): S897‑p, NMDAR1 iso7 (rat):
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  'brain, hippocampus', 293 (epithelial), QT-6 (fibroblast)
 Cellular systems studied:  cell lines, tissue
 Species studied:  human, quail, rat
 Comments:  transfected 293 and QT-6 cells, and hippocampal slices
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (cow)
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
phorbol ester no change compared to control
forskolin increase


Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.