Curated Information
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Curated Information Page
PubMed Id: 15743831 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Xiao GH, et al. (2005) The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression. Mol Cell Biol 25, 2384-94 15743831
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S518-p - Merlin (human)
Orthologous residues
Merlin (human): S518‑p, Merlin (mouse): S518‑p, Merlin (rat): S514‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Effect of modification (process):  cell cycle regulation, transcription, altered


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