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Curated Information Page
PubMed Id: 16097034 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Gevaert K, et al. (2005) Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. Proteomics 5, 3589-99 16097034
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
Download Sites

T7083-p - ACF7 (human)
Orthologous residues
ACF7 (human): T7083‑p, ACF7 iso2 (human): T5125‑p, ACF7 iso6 (human): T107‑p, ACF7 (mouse): T7043‑p, ACF7 iso4 (mouse): T5167‑p, ACF7 iso7 (mouse): T5028‑p, ACF7 (rat): T7040‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T50-p - ACTN1 (human)
Orthologous residues
ACTN1 (human): T50‑p, ACTN1 (mouse): T50‑p, ACTN1 iso3 (mouse): T50‑p, ACTN1 (rat): T50‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T65-p - ALDOA (human)
Orthologous residues
ALDOA (human): T65‑p, ALDOA (mouse): T65‑p, ALDOA (rat): T65‑p, ALDOA (rabbit): T65‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S115-p - COTL1 (human)
Orthologous residues
COTL1 (human): S115‑p, COTL1 (mouse): S115‑p, COTL1 (rat): S115‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S571-p - CTPS (human)
Orthologous residues
CTPS (human): S571‑p, CTPS (mouse): S571‑p, CTPS (rat): S571‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S573-p - CTPS (human)
Orthologous residues
CTPS (human): S573‑p, CTPS (mouse): S573‑p, CTPS (rat): S573‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S574-p - CTPS (human)
Orthologous residues
CTPS (human): S574‑p, CTPS (mouse): S574‑p, CTPS (rat): S574‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y321-p - DDX17 (human)
Orthologous residues
DDX17 (human): Y321‑p, DDX17 iso3 (human): Y242‑p, DDX17 (mouse): Y242‑p, DDX17 iso4 (mouse): Y242‑p, DDX17 (rat):
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y343-p - DDX3 (human)
Orthologous residues
DDX3 (human): Y343‑p, DDX3 (mouse): Y343‑p, DDX3 (rat): Y343‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y341-p - DDX3Y (human)
Orthologous residues
DDX3Y (human): Y341‑p, DDX3Y (mouse): Y342‑p, DDX3Y (rat): Y336‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y244-p - DDX5 (human)
Orthologous residues
DDX5 (human): Y244‑p, DDX5 (mouse): Y244‑p, DDX5 (rat): Y244‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T425-p - DPP3 (human)
Orthologous residues
DPP3 (human): T425‑p, DPP3 (mouse): T425‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S162-p - eEF1D (human)
Orthologous residues
eEF1D (human): S162‑p, eEF1D iso2 (human): S528‑p, eEF1D iso4 (human): S431‑p, eEF1D iso6 (human): , eEF1D (mouse): S162‑p, eEF1D iso2 (mouse): S138‑p, eEF1D iso3 (mouse): S541‑p, eEF1D iso4 (mouse): S157‑p, eEF1D (rat): S531‑p, eEF1D (rabbit): S162‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y978-p - EGFR (human)
Orthologous residues
EGFR (human): Y978‑p, EGFR iso5 (human): Y978‑p, EGFR (mouse): Y980‑p, EGFR (rat): Y979‑p, EGFR (pig): Y978‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S544-p - eIF2B-epsilon (human)
Orthologous residues
eIF2B‑epsilon (human): S544‑p, eIF2B‑epsilon (mouse): S540‑p, eIF2B‑epsilon (rat): S539‑p, eIF2B‑epsilon (rabbit): S544‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S39-p - eIF3C (human)
Orthologous residues
eIF3C (human): S39‑p, eIF3C (mouse): S39‑p, eIF3C (rat): S39‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S135-p - eIF5B (human)
Orthologous residues
eIF5B (human): S135‑p, eIF5B (mouse): S137‑p, eIF5B (rat): S137‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S137-p - eIF5B (human)
Orthologous residues
eIF5B (human): S137‑p, eIF5B (mouse): S139‑p, eIF5B (rat): S139‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S20-p - GM130 (human)
Orthologous residues
GM130 (human): S20‑p, GM130 iso3 (human): S20‑p, GM130 (mouse): S20‑p, GM130 iso3 (mouse): S20‑p, GM130 (rat): S20‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S217-p - GTF2F1 (human)
Orthologous residues
GTF2F1 (human): S217‑p, GTF2F1 (mouse): S217‑p, GTF2F1 (rat): S217‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S218-p - GTF2F1 (human)
Orthologous residues
GTF2F1 (human): S218‑p, GTF2F1 (mouse): S218‑p, GTF2F1 (rat): S218‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S221-p - GTF2F1 (human)
Orthologous residues
GTF2F1 (human): S221‑p, GTF2F1 (mouse): S221‑p, GTF2F1 (rat): S221‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S224-p - GTF2F1 (human)
Orthologous residues
GTF2F1 (human): S224‑p, GTF2F1 (mouse): S224‑p, GTF2F1 (rat): S224‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y83-p - HLAC (human)
Orthologous residues
HLAC (human): Y83‑p, HLAC iso2 (human): Y83‑p, HLAC iso5 (human): Y83‑p, HLAC iso7 (human): Y83‑p, HLAC iso14 (human): Y83‑p, HLAC iso15 (human): Y58‑p, HLAC iso20 (human): Y83‑p, HLAC (mouse): Y83‑p, HLAC iso7 (mouse): Y80‑p, HLAC iso21 (mouse): Y80‑p, HLAC iso22 (mouse): Y80‑p, HLAC iso23 (mouse): Y83‑p, HLAC iso25 (mouse): Y80‑p, HLAC iso26 (mouse): Y83‑p, HLAC iso27 (mouse): Y80‑p, HLAC (rat): Y59‑p, HLAC iso1 (rat): Y83‑p, HLAC iso3 (rat): Y80‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T138-p - hnRNP A1 (human)
Orthologous residues
hnRNP A1 (human): T138‑p, hnRNP A1 (mouse): T138‑p, hnRNP A1 iso2 (mouse): T138‑p, hnRNP A1 (rat): T138‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S82-p - HSP27 (human)
Orthologous residues
HSP27 (human): S82‑p, HSP27 (mouse): S86‑p, HSP27 (rat): S86‑p, HSP27 (pig): S84‑p, HSP27 (hamster): S90‑p, HSP27 (chicken): S80‑p, HSP27 (dog): S86‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S222-p - Ku70 (human)
Orthologous residues
Ku70 (human): S222‑p, Ku70 (mouse): T220‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S1213-p - MYO5A (human)
Orthologous residues
MYO5A (human): S1213‑p, MYO5A (mouse): S1213‑p, MYO5A (rat): S1213‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S149-p - NKAP (human)
Orthologous residues
NKAP (human): S149‑p, NKAP (mouse): S147‑p, NKAP (rat): S147‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S113-p - NUCKS (human)
Orthologous residues
NUCKS (human): S113‑p, NUCKS (mouse): S113‑p, NUCKS (rat): S113‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S63-p - OBTP (human)
Orthologous residues
OBTP (human): S63‑p, OBTP (mouse): S63‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T188-p - peptidase D (human)
Orthologous residues
peptidase D (human): T188‑p, peptidase D iso3 (human): T124‑p, peptidase D (mouse): T188‑p, peptidase D (rat): T188‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S782-p - Plectin-1 (human)
Orthologous residues
Plectin‑1 (human): S782‑p, Plectin‑1 iso2 (human): S672‑p, Plectin‑1 iso4 (human): S645‑p, Plectin‑1 iso6 (human): S649‑p, Plectin‑1 iso9 (human): S631‑p, Plectin‑1 (mouse): S790‑p, Plectin‑1 iso3 (mouse): S642‑p, Plectin‑1 iso6 (mouse): S671‑p, Plectin‑1 (rat): S785‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T157-p - PPIA (human)
Orthologous residues
PPIA (human): T157‑p, PPIA (mouse): T157‑p, PPIA (rat): T157‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y49-p - PSMD1 (human)
Orthologous residues
PSMD1 (human): Y49‑p, PSMD1 (mouse): Y49‑p, PSMD1 (rat): Y49‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S104-p - RPLP1 (human)
Orthologous residues
RPLP1 (human): S104‑p, RPLP1 (mouse): S104‑p, RPLP1 (rat): S104‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T838-p - SETDB1 (human)
Orthologous residues
SETDB1 (human): T838‑p, SETDB1 (mouse): T855‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T507-p - SLC7A5 (human)
Orthologous residues
SLC7A5 (human): T507‑p, SLC7A5 (mouse): T512‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S1568-p - SMARCA2 (human)
Orthologous residues
SMARCA2 (human): S1568‑p, SMARCA2 iso2 (human): S1550‑p, SMARCA2 (mouse): S1555‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S1572-p - SMARCA2 (human)
Orthologous residues
SMARCA2 (human): S1572‑p, SMARCA2 iso2 (human): S1554‑p, SMARCA2 (mouse): S1559‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S2-p - TRA2A (human)
Orthologous residues
TRA2A (human): S2‑p, TRA2A (mouse): S2‑p, TRA2A (rat): S2‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T100-p - TXN (human)
Orthologous residues
TXN (human): T100‑p, TXN (mouse): S100‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

S2-p - U2AF2 (human)
Orthologous residues
U2AF2 (human): S2‑p, U2AF2 (mouse): S2‑p, U2AF2 (rat): S2‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T508-p - Vinculin (human)
Orthologous residues
Vinculin (human): T508‑p, Vinculin iso2 (human): T508‑p, Vinculin (mouse): T508‑p, Vinculin (rat): T508‑p, Vinculin (chicken): T508‑p, Vinculin (dog): T508‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

T508-p - Vinculin iso2 (human)
Orthologous residues
Vinculin (human): T508‑p, Vinculin iso2 (human): T508‑p, Vinculin (mouse): T508‑p, Vinculin (rat): T508‑p, Vinculin (chicken): T508‑p, Vinculin (dog): T508‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  human

Y264-p - eEF2 (rabbit)
Orthologous residues
eEF2 (human): Y265‑p, eEF2 (mouse): Y265‑p, eEF2 (rat): Y265‑p, eEF2 (rabbit): Y264‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  HepG2 (hepatic)
 Cellular systems studied:  cell lines
 Species studied:  rabbit


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