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Curated Information Page
PubMed Id: 15951569 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Zhang Y, et al. (2005) Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. Mol Cell Proteomics 4, 1240-50 15951569
Only 100 sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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Protein GeneSymb ACC# Organism MW (Da) RSD SiteGrpId Mod Type Site Sequence
Ack TNK2 Q07912 human 114,569 Y859 448883 Phosphorylation KKVsstHyyLLPERP
Ack TNK2 Q07912 human 114,569 Y860 448884 Phosphorylation KVsstHyyLLPERPs
ACP1 ACP1 P24666 human 18,042 Y132 450718 Phosphorylation QLIIEDPyyGNDsDF
AFAP1L2 AFAP1L2 Q8N4X5 human 91,300 Y413 451085 Phosphorylation DPsPDHLysFRILHK
AHCYL1 AHCYL1 O43865 human 58,951 Y28 457506 Phosphorylation EIEDAEKysFMATVt
ANXA2 ANXA2 P07355 human 38,604 Y30 450390 Phosphorylation AyGsVkAytNFDAER
ARHGEF5 ARHGEF5 Q12774 human 176,800 Y1097 451622 Phosphorylation INsSQLLyQEySDVV
ARHGEF5 ARHGEF5 Q12774 human 176,800 Y1100 451623 Phosphorylation SQLLyQEySDVVLNk
BDP1 PTPN18 Q99952 human 50,482 Y389 449000 Phosphorylation SAEEAPLysKVtPRA
Brk PTK6 Q13882 human 51,834 Y447 450276 Phosphorylation RLSSFtsyENPT___
caveolin-1 CAV1 Q03135 human 20,472 Y6 455028 Phosphorylation __MSGGkyVDsEGHL
caveolin-1 CAV1 Q03135 human 20,472 Y14 448422 Phosphorylation VDsEGHLytVPIREQ
caveolin-1 CAV1 Q03135 human 20,472 Y25 457514 Phosphorylation IREQGNIykPNNkAM
Cbl CBL P22681 human 99,633 Y371 449753 Phosphorylation TQEQyELyCEMGSTF
Cbl CBL P22681 human 99,633 Y552 454835 Phosphorylation PPPPDRPySVGAESR
CCDC50 iso2 CCDC50 Q8IVM0 human 35,822 Y140 457507 Phosphorylation EFPATRAyADsyyyE
CCDC50 iso2 CCDC50 Q8IVM0 human 35,822 Y145 454594 Phosphorylation RAyADsyyyEDGGMk
CDK1 CDK1 P06493 human 34,095 Y15 447610 Phosphorylation EkIGEGtyGVVykGR
CDK1 CDK1 P06493 human 34,095 Y19 449488 Phosphorylation EGtyGVVykGRHkTT
cofilin 1 CFL1 P23528 human 18,502 Y89 449644 Phosphorylation yALyDAtyEtkEskk
cortactin CTTN Q14247 human 61,586 Y446 448776 Phosphorylation GtEPEPVysMEAADy
CTNND1 CTNND1 O60716 human 108,170 Y96 449495 Phosphorylation QDHSHLLystIPRMQ
CTNND1 CTNND1 O60716 human 108,170 Y321 455136 Phosphorylation PRRRLRsyEDMIGEE
CTNND1 CTNND1 O60716 human 108,170 Y334 450399 Phosphorylation EEVPsDQyyWAPLAQ
DCBLD2 DCBLD2 Q96PD2 human 85,035 Y750 454600 Phosphorylation PAPDELVyQVPQSTQ
desmoplakin 3 JUP P14923 human 81,745 Y20 451620 Phosphorylation VtEWQQtytyDsGIH
DSC2 DSC2 Q02487 human 99,962 Y823 457519 Phosphorylation VDNCRytysEWHsFT
EFNB2 EFNB2 P52799 human 36,923 Y304 451679 Phosphorylation DSVFCPHyEKVsGDy
EFNB2 EFNB2 P52799 human 36,923 Y330 455143 Phosphorylation PQsPANIyykV____
EGFR EGFR P00533 human 134,277 Y998 452118 Phosphorylation sPtDsNFyRALMDEE
EGFR EGFR P00533 human 134,277 Y1069 448056 Phosphorylation EDsFLQRyssDPtGA
EGFR EGFR P00533 human 134,277 Y1092 448057 Phosphorylation tFLPVPEyINQsVPK
EGFR EGFR P00533 human 134,277 S1166 452120 Phosphorylation QKGsHQIsLDNPDyQ
EGFR EGFR P00533 human 134,277 Y1172 448059 Phosphorylation IsLDNPDyQQDFFPk
ELMO2 ELMO2 Q96JJ3 human 82,615 Y48 450756 Phosphorylation WSLPNPEyyTLRYAD
ENO1 ENO1 P06733 human 47,169 Y44 448919 Phosphorylation sGAstGIyEALELRD
EphA1 EPHA1 P21709 human 108,127 Y781 457520 Phosphorylation LDDFDGtyEtQGGkI
EphA2 EPHA2 P29317 human 108,266 Y588 450859 Phosphorylation QLkPLktyVDPHtyE
EphA2 EPHA2 P29317 human 108,266 Y594 450860 Phosphorylation tyVDPHtyEDPNQAV
EphA2 EPHA2 P29317 human 108,266 Y772 450861 Phosphorylation EDDPEAtyttsGGkI
EphA2 EPHA2 P29317 human 108,266 Y921 457515 Phosphorylation ESIKMQQytEHFMAA
EphA2 EPHA2 P29317 human 108,266 Y930 457516 Phosphorylation EHFMAAGyTAIEKVV
EphB1 EPHB1 P54762 human 109,885 Y594 449995 Phosphorylation GSPGMkIyIDPFtyE
EphB1 EPHB1 P54762 human 109,885 Y600 450470 Phosphorylation IyIDPFtyEDPNEAV
EphB3 EPHB3 P54753 human 110,330 Y608 451547 Phosphorylation IAPGMKVyIDPFtyE
EphB3 EPHB3 P54753 human 110,330 Y614 448275 Phosphorylation VyIDPFtyEDPNEAV
EPS15 EPS15 P42566 human 98,656 Y849 450484 Phosphorylation NFANFSAyPsEEDMI
ERK1 MAPK3 P27361 human 43,136 Y204 447543 Phosphorylation HtGFLtEyVAtRWyR
ERK2 MAPK1 P28482 human 41,390 Y187 447594 Phosphorylation HtGFLtEyVAtRWyR
FAK PTK2 Q05397 human 119,233 Y576 447889 Phosphorylation RyMEDstyyKAsKGK
FRK FRK P42685 human 58,254 Y497 451535 Phosphorylation YFETDssysDANNFI
G6PD G6PD P11413 human 59,257 Y507 451668 Phosphorylation GFQyEGtyKWVNPHk
GAREM GAREM Q9H706 human 97,186 Y453 450613 Phosphorylation PGKSELPyEELWLEE
GIT1 GIT1 Q9Y2X7 human 84,341 Y545 448965 Phosphorylation ELEDDAIysVHVPAG
GSK3A GSK3A P49840 human 50,981 Y279 447723 Phosphorylation RGEPNVsyICsRyyR
HER2 ERBB2 P04626 human 137,910 Y1248 447614 Phosphorylation PTAENPEyLGLDVPV
InsR INSR P06213 human 156,333 Y1185 447680 Phosphorylation FGMTRDIyEtDyyRK
InsR INSR P06213 human 156,333 Y1189 447681 Phosphorylation RDIyEtDyyRKGGKG
ITGB4 ITGB4 P16144 human 202,167 Y1207 451665 Phosphorylation GAQGEGPyssLVSCR
ITSN2 ITSN2 Q9NZM3 human 193,461 Y553 457110 Phosphorylation EYQNKLIyLVPEKQL
Lck LCK P06239 human 58,001 Y394 447822 Phosphorylation RLIEDNEytAREGAK
LPP LPP Q93052 human 65,746 Y300 448948 Phosphorylation QGRyyEGyyAAGPGy
LPP LPP Q93052 human 65,746 Y301 448949 Phosphorylation GRyyEGyyAAGPGyG
MARVELD2 MARVELD2 Q8N4S9 human 64,168 Y23 454618 Phosphorylation EVPSDLPyQDttIRT
Nck1 NCK1 P16333 human 42,864 Y105 448953 Phosphorylation VDPGERLyDLNMPAy
P130Cas BCAR1 P56945 human 93,372 Y249 448721 Phosphorylation APGPQDIyDVPPVRG
P130Cas BCAR1 P56945 human 93,372 Y327 448780 Phosphorylation PLLREEtyDVPPAFA
PAR3-alpha PARD3 Q8TEW0 human 151,423 Y1127 457508 Phosphorylation GHMMDALyAQVKKPR
PHLPP PHLPP1 O60346 human 184,672 Y1712 457517 Phosphorylation QLDQLPDyyDTPL__
PIK3R1 PIK3R1 P27986 human 83,598 Y607 448136 Phosphorylation NENtEDQysLVEDDE
PIK3R2 PIK3R2 O00459 human 81,545 Y464 449572 Phosphorylation sREyDQLyEEytRTS
plakophilin 3 PKP3 Q9Y446 human 87,082 Y84 449514 Phosphorylation RGTSRGQyHtLQAGF
plakophilin 3 PKP3 Q9Y446 human 87,082 Y195 451533 Phosphorylation PGGLDDRysLVsEQL
plakophilin 4 PKP4 Q99569 human 131,868 Y478 448891 Phosphorylation ALNttAtyAEPyRPI
PLCG1 PLCG1 P19174 human 148,532 Y771 448575 Phosphorylation IGtAEPdyGALyEGR
PLCG1 PLCG1 P19174 human 148,532 Y775 448907 Phosphorylation EPdyGALyEGRNPGF
PLCG1 PLCG1 P19174 human 148,532 Y783 447667 Phosphorylation EGRNPGFyVEANPMP
plectin 1 PLEC Q15149 human 531,791 Y4611 454955 Phosphorylation AAQSTkGyysPysVs
PLEKHA5 PLEKHA5 Q9HAU0 human 127,464 Y128 457510 Phosphorylation MINEAsNyNVtsDyA
PLEKHA5 PLEKHA5 Q9HAU0 human 127,464 Y134 457511 Phosphorylation NyNVtsDyAVHPMsP
PLEKHA6 PLEKHA6 Q9Y2H5 human 117,128 Y492 454634 Phosphorylation PPRsEDIyADPAAyV
PRP4 PRPF4B Q13523 human 116,987 Y849 449515 Phosphorylation ADNDItPyLVsRFyR
PTPRA PTPRA P18433 human 90,600 Y798 447613 Phosphorylation yIDAFsDyANFK___
PTRF PTRF Q6NZI2 human 43,476 Y308 450709 Phosphorylation FtPDHVVyARSKtAV
PXN iso2 PXN P49023-2 human 60,967 Y118 448604 Phosphorylation VGEEEHVysFPNKQK
RAIG1 GPRC5A Q8NFJ5 human 40,251 Y317 451750 Phosphorylation EEtGDtLyAPystHF
RBCK1 RBCK1 Q9BYM8 human 57,572 Y330 454647 Phosphorylation CPFIDNTysCsGKLL
Rin1 RIN1 Q13671 human 84,099 Y36 450778 Phosphorylation kPAQDPLyDVPNAsG
SgK223 SGK223 Q86YV5 human 149,311 Y411 449701 Phosphorylation ATQPEPIyAEsTKRK
Shb SHB Q15464 human 55,042 Y246 450867 Phosphorylation KVtIADDysDPFDAK
Shc1 SHC1 P29353 human 62,822 Y349 448509 Phosphorylation EEPPDHQyyNDFPGK
Shc1 SHC1 P29353 human 62,822 Y350 448510 Phosphorylation EPPDHQyyNDFPGKE
Shc1 SHC1 P29353 human 62,822 Y427 448511 Phosphorylation ELFDDPsyVNVQNLD
SHIP-2 INPPL1 O15357 human 138,599 Y986 448889 Phosphorylation NsFNNPAyyVLEGVP
SHIP-2 INPPL1 O15357 human 138,599 S1003 448890 Phosphorylation LLPPEPPsPARAPVP
SHP-2 PTPN11 Q06124 human 68,436 Y62 449573 Phosphorylation KIQNtGDyyDLyGGE
SKT KIAA1217 Q5T5P2 human 214,116 Y393 451662 Phosphorylation MyRNEGFyADPyLyH
SLC38A2 SLC38A2 Q9HAV3 human 56,026 Y20 457509 Phosphorylation PDEDsssyssNsDFN
STAM1 STAM Q92783 human 59,180 Y381 457512 Phosphorylation LMNEDPMysMyAKLQ
STAM2 STAM2 O75886 human 58,164 Y371 449670 Phosphorylation LVNEAPVysVysKLH

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