Curated Information
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Curated Information Page
PubMed Id: 8444886 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Robbins DJ, et al. (1993) Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. J Biol Chem 268, 5097-106 8444886
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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T202-p - ERK1 (human) ▲
Orthologous residues
ERK1 (human): T202‑p, ERK1 (mouse): T203‑p, ERK1 (rat): T203‑p, ERK1 (hamster): T192‑p
Characterization
 Enzymes shown to modify site in vitro: 
Type Enzyme
KINASE MEK1 (rabbit)
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced

Y204-p - ERK1 (human) ▲
Orthologous residues
ERK1 (human): Y204‑p, ERK1 (mouse): Y205‑p, ERK1 (rat): Y205‑p, ERK1 (hamster): Y194‑p
Characterization
 Enzymes shown to modify site in vitro: 
Type Enzyme
KINASE MEK1 (rabbit)
KINASE ERK1 (human)
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced

Y185-p - ERK2 (mouse) ▲
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p
Characterization
 Enzymes shown to modify site in vitro: 
Type Enzyme
KINASE ERK2 (rat)
KINASE MEK1 (rabbit)
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced

T183-p - ERK2 (rat) ▲
Orthologous residues
ERK2 (human): T185‑p, ERK2 (mouse): T183‑p, ERK2 (rat): T183‑p, ERK2 (chicken): T193‑p
Characterization
 Enzymes shown to modify site in vitro: 
Type Enzyme
KINASE MEK1 (rabbit)
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced

Y185-p - ERK2 (rat) ▲
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p


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