Curated Information
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PubMed Id: 11409731 
Guizzetti M, Costa LG (2001) Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells. Neuroreport 12, 1639-42 11409731
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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S473-p - Akt1 (human)
Orthologous residues
Akt1 (human): S473‑p, Akt1 (mouse): S473‑p, Akt1 (rat): S473‑p, Akt1 (fruit fly): S586‑p, Akt1 (cow): S473‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  1321N1 (glial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
carbachol increase
atropine carbachol inhibit treatment-induced increase
4-DAMP carbachol inhibit treatment-induced increase
gallamine carbachol no effect upon treatment-induced increase
PTX carbachol no effect upon treatment-induced increase
LY294002 carbachol inhibit treatment-induced increase
wortmannin carbachol inhibit treatment-induced increase
PD98059 carbachol no effect upon treatment-induced increase
U0126 carbachol no effect upon treatment-induced increase
GF109203X carbachol no effect upon treatment-induced increase
rapamycin carbachol no effect upon treatment-induced increase


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