Curated Information
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Curated Information Page
PubMed Id: 11836526 
Fujita Y, et al. (2002) Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol 4, 222-31 11836526
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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Y755-p - CDH1 (mouse)
Orthologous residues
CDH1 (human): Y753‑p, CDH1 (mouse): Y755‑p, CDH1 (rat): Y757‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody
 Relevant cell lines - cell types - tissues:  293 (epithelial), MDCK (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  dog, human
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
CBLL1 (mouse) Induces protein stabilization co-immunoprecipitation

Y756-p - CDH1 (mouse)
Orthologous residues
CDH1 (human): Y754‑p, CDH1 (mouse): Y756‑p, CDH1 (rat): Y758‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody
 Relevant cell lines - cell types - tissues:  293 (epithelial), MDCK (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  dog, human
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
CBLL1 (mouse) Induces protein stabilization co-immunoprecipitation


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