|
Orthologous residues
|
|
Cx43 (human): S368‑p, Cx43 (mouse): S368‑p, Cx43 (rat): S368‑p, Cx43 (rabbit): S368‑p, Cx43 (hamster): S368‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
2D analysis, [32P] bio-synthetic labeling, phosphoamino acid analysis
|
|
Relevant cell lines - cell types - tissues:
fibroblast-skin, T51B (epithelial)
|
|
Cellular systems studied:
cell lines, primary cultured cells
|
|
Species studied:
mouse, rat
|
|
Enzymes shown to modify site in vitro:
|
|
|
|
Upstream Regulation
|
|
Potential in vivo enzymes for site:
|
|
Type
|
Enzyme
|
Evidence
|
Notes
|
|
KINASE
|
PKCA (rat)
|
pharmacological activator of upstream enzyme
|
|
|
KINASE
|
PKCA (mouse)
|
pharmacological activator of upstream enzyme
|
|
|
|
Treatments, proteins and their effect on site modification:
|
|
Treatments
|
Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
phorbol ester
|
|
|
|
increase
|
|
|
|
Downstream Regulation
|
|
Effect of modification (function):
inhibition
|
