Curated Information
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Curated Information Page
PubMed Id: 11514606 
Gong Q, et al. (2001) Requirement for tyrosine residues 315 and 319 within zeta chain-associated protein 70 for T cell development. J Exp Med 194, 507-18 11514606
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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Y315-p - ZAP70 (human)
Orthologous residues
ZAP70 (human): Y315‑p, ZAP70 (mouse): Y314‑p, ZAP70 (rat): Y310‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody
 Relevant cell lines - cell types - tissues:  T lymphocyte-thymus
 Cellular systems studied:  primary cells
 Species studied:  mouse
Downstream Regulation
 Comments:  role in T cell selection in thymus

Y319-p - ZAP70 (human)
Orthologous residues
ZAP70 (human): Y319‑p, ZAP70 (mouse): Y318‑p, ZAP70 (rat): Y314‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody
 Relevant cell lines - cell types - tissues:  T lymphocyte-thymus
 Cellular systems studied:  primary cells
 Species studied:  mouse
Downstream Regulation
 Comments:  role in T cell selection in thymus

Y493-p - ZAP70 (human)
Orthologous residues
ZAP70 (human): Y493‑p, ZAP70 (mouse): Y492‑p, ZAP70 (rat): Y488‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody
 Relevant cell lines - cell types - tissues:  T lymphocyte-thymus
 Cellular systems studied:  primary cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced


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