Curated Information
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Curated Information Page
PubMed Id: 11423984 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Minamoto T, et al. (2001) Distinct pattern of p53 phosphorylation in human tumors. Oncogene 20, 3341-7 11423984
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
Download Sites

S6-p - p53 (human) ▲
Orthologous residues
p53 (human): S6‑p, p53 (mouse): S6‑p, p53 iso2 (mouse): S9‑p, p53 (rat): S6‑p, p53 (rabbit): S6‑p, p53 (monkey): S6‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  A2182, Aspc1 (pancreatic), Colo-320 (intestinal), HT116, NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase

S9-p - p53 (human) ▲
Orthologous residues
p53 (human): S9‑p, p53 (mouse): S9‑p, p53 iso2 (mouse): S12‑p, p53 (rat): S9‑p, p53 (rabbit): S9‑p, p53 (monkey): S9‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  A2182, Aspc1 (pancreatic), Colo-320 (intestinal), NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase

S15-p - p53 (human) ▲
Orthologous residues
p53 (human): S15‑p, p53 (mouse): S15‑p, p53 iso2 (mouse): S18‑p, p53 (rat): S15‑p, p53 (rabbit): S15‑p, p53 (monkey): S15‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  A2182, Aspc1 (pancreatic), Colo-320 (intestinal), HT116, NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase

S20-p - p53 (human) ▲
Orthologous residues
p53 (human): S20‑p, p53 (mouse): S20‑p, p53 iso2 (mouse): S23‑p, p53 (rat): S20‑p, p53 (rabbit): S20‑p, p53 (monkey): S20‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  Aspc1 (pancreatic), Colo-320 (intestinal), NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase

S37-p - p53 (human) ▲
Orthologous residues
p53 (human): S37‑p, p53 (mouse): S34‑p, p53 iso2 (mouse): S37‑p, p53 (rat): S39‑p, p53 (rabbit): N37‑p, p53 (monkey): S37‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  A2182, Aspc1 (pancreatic), Colo-320 (intestinal), HT116, NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase

T81-p - p53 (human) ▲
Orthologous residues
p53 (human): T81‑p, p53 (mouse): G75‑p, p53 iso2 (mouse): G78‑p, p53 (rat): A79‑p, p53 (rabbit): A78‑p, p53 (monkey): T81‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  A2182, Aspc1 (pancreatic), Colo-320 (intestinal), HT116, NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase

S371-p - p53 (human) ▲
Orthologous residues
p53 (human): S371‑p, p53 (mouse): T365‑p, p53 iso2 (mouse): ‑, p53 (rat): T369‑p, p53 (rabbit): A369‑p, p53 (monkey): S371‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  Aspc1 (pancreatic), Colo-320 (intestinal), NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase

S392-p - p53 (human) ▲
Orthologous residues
p53 (human): S392‑p, p53 (mouse): S386‑p, p53 iso2 (mouse): ‑, p53 (rat): S390‑p, p53 (rabbit): S390‑p, p53 (monkey): S392‑p
Characterization
 Methods used to characterize site in vivo:  phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  Aspc1 (pancreatic), Colo-320 (intestinal), NCI-H596 (pulmonary), OM431, OSA (bone cell), SW680 (intestinal), WM4, WM5, WM793
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
UV increase


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