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Orthologous residues
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Chk2 (human): T68‑p, Chk2 iso12 (human): T68‑p, Chk2 (mouse): T77‑p, Chk2 (rat): T76‑p
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Characterization
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Methods used to characterize site in vivo:
2D analysis, [32P] bio-synthetic labeling, mutation of modification site, phospho-antibody
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Relevant cell lines - cell types - tissues:
293T (epithelial), SH-SY5Y (neural crest)
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Cellular systems studied:
cell lines
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Species studied:
human, mouse
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Enzymes shown to modify site in vitro:
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Downstream Regulation
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Effect of modification (function):
enzymatic activity, induced
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