Curated Information

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Curated Information Page

PubMed Id: 15705584

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Debidda M, et al. (2005) A role of STAT3 in Rho GTPase-regulated cell migration and proliferation. J Biol Chem 280, 17275-85 15705584

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

Y705-p - STAT3 (mouse)

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Orthologous residues

STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Relevant cell lines - cell types - tissues: MEF (fibroblast) [IGF1R (mouse)]

Cellular systems studied: cell lines

Species studied: mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
IL-6				increase
Y27632				decrease

Downstream Regulation

Effect of modification (function): intracellular localization

Effect of modification (process): cell growth, altered

S727-p - STAT3 (mouse)

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