Chen L, Feany MB (2005) Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat Neurosci 8, 657-63 15834418

This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2015, 43:D512-20). To learn more about the scope of PhosphoSitePlus®, click here.

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S129-p - SNCA (human) ▲

Modsite: NEAyEMPsEEGyQDy SwissProt Entrez-Gene Orthologous residues SNCA (human): S129‑p, SNCA (mouse): S129‑p, SNCA (rat): S129‑p Characterization Methods used to characterize site in vivo:  mutation of modification site, phospho-antibody Relevant cell lines - cell types - tissues:  'neuron, bipolar' Cellular systems studied:  primary cells Species studied:  fruit fly Downstream Regulation Comments:  enhances SNCA toxicity