Curated Information

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Curated Information Page

PubMed Id: 11850821

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Zamo A, et al. (2002) Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Oncogene 21, 1038-47 11850821

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

Y705-p - STAT3 (human)

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Orthologous residues

STAT3 (human): Y705‑p, STAT3 iso2 (human): Y704‑p, STAT3 iso3 (human): Y705‑p, STAT3 (mouse): Y705‑p, STAT3 iso2 (mouse): Y705‑p, STAT3 iso3 (mouse): Y704‑p, STAT3 (rat): Y705‑p, STAT3 (cow): Y705‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Disease tissue studied: lymphoma, anaplastic large cell lymphoma

Relevant cell lines - cell types - tissues: DHL (T lymphocyte), Karpas-299 (T lymphocyte)

Cellular systems studied: cell lines

Species studied: human

Upstream Regulation

Potential in vivo enzymes for site:

Type	Enzyme	Evidence	Notes
KINASE	ALK (human)	transfection of dominant-negative enzyme, transfection of wild-type enzyme

S727-p - STAT3 (human)

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