Curated Information
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Curated Information Page
PubMed Id: 11090544 
Oelze M, et al. (2000) Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction. Circ Res 87, 999-1005 11090544
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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S239-p - VASP (human)
Orthologous residues
VASP (human): S239‑p, VASP (mouse): S235‑p, VASP (rat): S236‑p
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  aorta
 Cellular systems studied:  tissue
 Species studied:  rabbit
 Comments:  hyperlipidemic Watanabe rabbits
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
N-nitro-L-arginine decrease
DDTC decrease
hyperlipidemia decrease hyperlipidemic Watanabe rabbits
irbesartan hyperlipidemia inhibit treatment-induced decrease
irbesartan no change compared to control
SNP increase
hyperlipidemia SNP augment treatment-induced increase

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