|
Orthologous residues
|
|
VASP (human): S239‑p, VASP (mouse): S235‑p, VASP (rat): S236‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
phospho-antibody, western blotting
|
|
Relevant cell lines - cell types - tissues:
aorta
|
|
Cellular systems studied:
tissue
|
|
Species studied:
rabbit
|
|
Comments:
hyperlipidemic Watanabe rabbits
|
|
Upstream Regulation
|
|
Treatments, proteins and their effect on site modification:
|
|
Treatments
|
Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
N-nitro-L-arginine
|
|
|
|
decrease
|
|
|
DDTC
|
|
|
|
decrease
|
|
|
hyperlipidemia
|
|
|
|
decrease
|
hyperlipidemic Watanabe rabbits
|
|
irbesartan
|
hyperlipidemia
|
|
|
inhibit treatment-induced decrease
|
|
|
irbesartan
|
|
|
|
no change compared to control
|
|
|
SNP
|
|
|
|
increase
|
|
|
hyperlipidemia
|
SNP
|
|
|
augment treatment-induced increase
|
|
|
