Curated Information
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Curated Information Page
PubMed Id: 11719502 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Xiao GH, Beeser A, Chernoff J, Testa JR (2002) p21-activated kinase links Rac/Cdc42 signaling to merlin. J Biol Chem 277, 883-6 11719502
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S518-p - Merlin (human)
Orthologous residues
Merlin (human): S518‑p, Merlin (mouse): S518‑p, Merlin (rat): S514‑p
Characterization
 Methods used to characterize site in vivo electrophoretic mobility shift, mutation of modification site
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE PAK1 (human)
Upstream Regulation
 Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE PAK1 (human) transfection of wild-type enzyme, transfection of dominant-negative enzyme


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