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Orthologous residues
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MUC1 (human): T1224‑p, MUC1 iso2 (human): T233‑p, MUC1 iso6 (human): T199‑p, MUC1 (mouse): T599‑p, MUC1 (rat): T43‑p
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Characterization
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|
Methods used to characterize site in vivo:
mutation of modification site
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|
Relevant cell lines - cell types - tissues:
293 (epithelial), HCT116 (intestinal)
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|
Cellular systems studied:
cell lines
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Species studied:
human
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Enzymes shown to modify site in vitro:
|
|
|
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Upstream Regulation
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|
Potential in vivo enzymes for site:
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|
Type
|
Enzyme
|
Evidence
|
Notes
|
|
KINASE
|
PKCD (human)
|
co-immunoprecipitation
|
|
|
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Downstream Regulation
|
|
Effect of modification (function):
molecular association, regulation
|
|
Effect of modification (process):
cell growth, altered
|
