Curated Information

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PubMed Id: 15735306

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Wang X, et al. (2005) Regulation of neuroprotective activity of myocyte-enhancer factor 2 by cAMP-protein kinase A signaling pathway in neuronal survival. J Biol Chem 280, 16705-13 15735306

T20-p - MEF2C (mouse)

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Orthologous residues

MEF2C (human): T20‑p, MEF2C iso3 (human): T20‑p, MEF2C iso4 (human): T20‑p, MEF2C (mouse): T20‑p, MEF2C iso4 (mouse): T20‑p, MEF2C (rat): T20‑p

Characterization

Methods used to characterize site in vivo: mutation of modification site

Relevant cell lines - cell types - tissues: 'neuron, cerebellar granule'-brain

Cellular systems studied: primary cells

Species studied: rat

Enzymes shown to modify site in vitro:

Type	Enzyme
KINASE	PKACa (human)

Downstream Regulation

Effect of modification (process): apoptosis, inhibited, transcription, altered

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