Curated Information
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Curated Information Page
PubMed Id: 12475985 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Ukomadu C, Dutta A (2003) Inhibition of cdk2 activating phosphorylation by mevastatin. J Biol Chem 278, 4840-6 12475985
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T160-p - CDK2 (human)
Orthologous residues
CDK2 (human): T160‑p, CDK2 (mouse): T160‑p, CDK2 (rat): T160‑p
Characterization
 Methods used to characterize site in vivo [32P] bio-synthetic labeling, electrophoretic mobility shift
 Relevant cell lines - cell types - tissues:  PC3 (prostate cell)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
mevastatin decrease
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced


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