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Orthologous residues
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Bik (human): T33‑p, Bik (mouse): ‑, Bik (rat): ‑
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Characterization
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Methods used to characterize site in vivo:
mutation of modification site
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|
Relevant cell lines - cell types - tissues:
MCF-7 (breast cell), MDA-MB231 (breast cell), MDA-MB468 (breast cell), NCI-H1299 (pulmonary), PANC-1 (pancreatic), PC3 (prostate cell)
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Cellular systems studied:
cell lines
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Species studied:
human
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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|
Modification regulates interactions with:
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|
Interacting molecule
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Interacting domains
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Effect
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Consequences (function)
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Consequences (process)
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Detection assays
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|
Bcl-2 (human)
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Induces
|
|
apoptosis, altered
|
co-immunoprecipitation, electrophoretic visualization
|
|
Bcl-xL (human)
|
|
Induces
|
|
apoptosis, altered
|
co-immunoprecipitation, electrophoretic visualization
|
|
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|
