Curated Information
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Curated Information Page
PubMed Id: 11306463 
Pan W, Cox S, Hoess RH, Grafström RH (2001) A cyclin D1/cyclin-dependent kinase 4 binding site within the C domain of the retinoblastoma protein. Cancer Res 61, 2885-91 11306463
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S780-p - Rb (human)
Orthologous residues
Rb (human): S780‑p, Rb (mouse): S773‑p, Rb (rat): S772‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK4 (human)
 Comments:  mutation of LXCXE binding site prevents CDK4 phosphorylation of S807/811, but not S780 and S811.

S795-p - Rb (human)
Orthologous residues
Rb (human): S795‑p, Rb (mouse): S788‑p, Rb (rat): S787‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK4 (human)
 Comments:  mutation of LXCXE binding site prevents CDK4 phosphorylation of S807/811, but not S780 and S811.

S807-p - Rb (human)
Orthologous residues
Rb (human): S807‑p, Rb (mouse): S800‑p, Rb (rat): S799‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK4 (human)
 Comments:  mutation of LXCXE binding site prevents CDK4 phosphorylation of S807/811, but not S780 and S811.

S811-p - Rb (human)
Orthologous residues
Rb (human): S811‑p, Rb (mouse): S804‑p, Rb (rat): S803‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK4 (human)
 Comments:  mutation of LXCXE binding site prevents CDK4 phosphorylation of S807/811, but not S780 and S811.


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