|
Orthologous residues
|
|
PBK (human): T9‑p, PBK (mouse): T9‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
mutation of modification site, phospho-antibody
|
|
Relevant cell lines - cell types - tissues:
COS (fibroblast), HeLa (cervical)
|
|
Cellular systems studied:
cell lines
|
|
Species studied:
human, monkey
|
|
Enzymes shown to modify site in vitro:
|
|
|
|
Downstream Regulation
|
|
Effect of modification (function):
molecular association, regulation
|
|
Effect of modification (process):
cytoskeletal reorganization
|
|
Modification regulates interactions with:
|
|
Interacting molecule
|
Interacting domains
|
Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
CCNB1 (human)
|
|
Induces
|
|
|
co-immunoprecipitation
|
|
CDK1 (human)
|
|
Induces
|
|
|
co-immunoprecipitation
|
|
TUBA4A (human)
|
|
Induces
|
|
|
co-immunoprecipitation
|
|
