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Orthologous residues
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|
ITGB3 (human): S778‑p, ITGB3 iso5 (human): ‑, ITGB3 (mouse): S777‑p
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Characterization
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|
Methods used to characterize site in vivo:
mutation of modification site
|
|
Relevant cell lines - cell types - tissues:
CHO (fibroblast), endothelial-bone marrow
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|
Cellular systems studied:
cell lines, primary cultured cells
|
|
Species studied:
hamster, human
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|
Downstream Regulation
|
|
Effect of modification (function):
molecular association, regulation, protein conformation
|
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Effect of modification (process):
cell adhesion, altered
|
|
Modification regulates interactions with:
|
|
Interacting molecule
|
Interacting domains
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Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
ITGA4 (human)
|
|
Disrupts
|
|
|
functional assay
|
|
