Curated Information

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PubMed Id: 15324364

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Information from this record has been curated, but not yet edited in PhosphoSitePlus^® and may be incomplete.

de Leon MJ, et al. (2004) MRI and CSF studies in the early diagnosis of Alzheimer's disease. J Intern Med 256, 205-23 15324364

T231-p - tau iso8 (human)

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Orthologous residues

tau (human): T548‑p, tau iso2 (human): T173‑p, tau iso3 (human): T137‑p, tau iso5 (human): T231‑p, tau iso6 (human): T173‑p, tau iso8 (human): T231‑p, tau (mouse): T523‑p, tau iso3 (mouse): T220‑p, tau iso7 (mouse): T180‑p, tau (rat): T542‑p, tau (cow): T238‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Relevant cell lines - cell types - tissues: cerebrospinal fluid

Cellular systems studied: tissue

Species studied: human

Downstream Regulation

Comments: Alzheimers Disease patient T231 phosphorylation is inversely correlated with hippocampal volume.

Associated Diseases

Diseases:	Alterations:	Comments:
Alzheimer's disease	increased	AD diagnostic tool

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