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Orthologous residues
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|
5‑LO (human): S524‑p, 5‑LO (mouse): S524‑p, 5‑LO (rat): S523‑p
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Characterization
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Methods used to characterize site in vivo:
mutation of modification site, phospho-antibody
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|
Relevant cell lines - cell types - tissues:
3T3 (fibroblast) [5-LO (human)], 3T3 (fibroblast) [PKIA (mouse)]
|
|
Cellular systems studied:
cell lines
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|
Species studied:
mouse
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|
Enzymes shown to modify site in vitro:
|
|
|
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Upstream Regulation
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|
Potential in vivo enzymes for site:
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|
Type
|
Enzyme
|
Evidence
|
Notes
|
|
KINASE
|
PKACA (mouse)
|
transfection of wild-type enzyme
|
|
|
|
Downstream Regulation
|
|
Effect of modification (function):
enzymatic activity, inhibited
|
