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Orthologous residues
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CSFR (human): Y923‑p, CSFR (mouse): Y921‑p
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Characterization
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Methods used to characterize site in vivo:
mutation of modification site
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Relevant cell lines - cell types - tissues:
3T3 (fibroblast)
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Cellular systems studied:
cell lines
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Species studied:
mouse
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Enzymes shown to modify site in vitro:
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Effect of modification (process):
cell growth, altered, cytoskeletal reorganization
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Modification regulates interactions with:
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Interacting molecule
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Interacting domains
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Effect
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Consequences (function)
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Consequences (process)
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Detection assays
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Grb2 (mouse)
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SH2
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Induces
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yeast two-hybrid, pull-down assay
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Comments:
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