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Orthologous residues
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CD4 (human): S433‑p, CD4 iso2 (human): S254‑p, CD4 (mouse): S432‑p
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Characterization
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|
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling, mutation of modification site, phosphopeptide mapping
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|
Relevant cell lines - cell types - tissues:
HeLa (cervical)
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Cellular systems studied:
cell lines
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Species studied:
human
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Upstream Regulation
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Treatments, proteins and their effect on site modification:
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Treatments
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Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
phorbol ester
|
|
|
|
increase
|
|
|
|
Downstream Regulation
|
|
Effect of modification (function):
protein degradation, receptor internalization, altered
|
