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Orthologous residues
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|
Pim1 (human): Y309‑p, Pim1 (mouse): Y302‑p, Pim1 (rat): Y218‑p
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|
Characterization
|
|
Methods used to characterize site in vivo:
mutation of modification site, phospho-antibody
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|
Relevant cell lines - cell types - tissues:
22Rv1 (prostate cell), LNCaP (prostate cell), PC3 (prostate cell)
|
|
Cellular systems studied:
cell lines
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|
Species studied:
human
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|
Upstream Regulation
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|
Potential in vivo enzymes for site:
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|
Type
|
Enzyme
|
Evidence
|
Notes
|
|
KINASE
|
Etk (mouse)
|
transfection of inactive enzyme, transfection of wild-type enzyme
|
|
|
|
Downstream Regulation
|
|
Effect of modification (function):
activation
|
