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Orthologous residues
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AQP2 (human): S256‑p, AQP2 (mouse): S256‑p, AQP2 (rat): S256‑p
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Characterization
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Methods used to characterize site in vivo:
mutation of modification site
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Relevant cell lines - cell types - tissues:
LLC-PK1 (epithelial)
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Cellular systems studied:
cell lines
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Species studied:
pig
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Upstream Regulation
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Treatments, proteins and their effect on site modification:
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Treatments
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Referenced Treatments
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Manipulated Protein
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Referenced Protein
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Effect
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Notes
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vasopressin
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|
|
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no change compared to control
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Vasopressin did not cause AQP2 to relocate to the plasma membrane in S256A mutant.
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|
|
|
|
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no change compared to control
|
mBeta CD treatment induced APQ2 redistribution in S256A mutant.
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