Curated Information
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Curated Information Page
PubMed Id: 14557263 
Tu Y, Nayak SK, Woodson J, Ross EM (2003) Phosphorylation-regulated inhibition of the Gz GTPase-activating protein activity of RGS proteins by synapsin I. J Biol Chem 278, 52273-81 14557263
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
Download Sites

S9-p - SYN1 (rat)
Orthologous residues
SYN1 (human): S9‑p, SYN1 (mouse): S9‑p, SYN1 iso1 (mouse): S9‑p, SYN1 iso3 (mouse): S9‑p, SYN1 (rat): S9‑p, SYN1 (cow): S9‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  SF9
 Cellular systems studied:  cell lines
 Species studied:  insect
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE PKACA (rat)
KINASE PAK1 (rat)
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
okadaic acid increase
Downstream Regulation
 Effect of modification (function):  activity, induced
 Comments:  GAP activity

S62-p - SYN1 (rat)
Orthologous residues
SYN1 (human): S62‑p, SYN1 (mouse): S62‑p, SYN1 iso1 (mouse): S62‑p, SYN1 iso3 (mouse): S62‑p, SYN1 (rat): S62‑p, SYN1 (cow): S62‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  SF9
 Cellular systems studied:  cell lines
 Species studied:  insect
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
okadaic acid increase

S67-p - SYN1 (rat)
Orthologous residues
SYN1 (human): S67‑p, SYN1 (mouse): S67‑p, SYN1 iso1 (mouse): S67‑p, SYN1 iso3 (mouse): S67‑p, SYN1 (rat): S67‑p, SYN1 (cow): S67‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  SF9
 Cellular systems studied:  cell lines
 Species studied:  insect
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
okadaic acid increase

S549-p - SYN1 (rat)
Orthologous residues
SYN1 (human): S551‑p, SYN1 (mouse): S551‑p, SYN1 iso1 (mouse): S551‑p, SYN1 iso3 (mouse): S551‑p, SYN1 (rat): S549‑p, SYN1 (cow): S551‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  SF9
 Cellular systems studied:  cell lines
 Species studied:  insect
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
okadaic acid increase

S603-p - SYN1 (rat)
Orthologous residues
SYN1 (human): S605‑p, SYN1 (mouse): S605‑p, SYN1 iso1 (mouse): S605‑p, SYN1 iso3 (mouse): S577‑p, SYN1 (rat): S603‑p, SYN1 (cow): S605‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  SF9
 Cellular systems studied:  cell lines
 Species studied:  insect
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
okadaic acid increase


Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.