Curated Information
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PubMed Id: 24142690 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Matsuyama M, et al. (2013) Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells. J Biol Chem 288, 35626-35 24142690
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S7-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S7‑p, Vimentin (mouse): S7‑p, Vimentin (rat): S7‑p, Vimentin (hamster): S7‑p, Vimentin (cow): S7‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S26-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S26‑p, Vimentin (mouse): S26‑p, Vimentin (rat): S26‑p, Vimentin (hamster): S26‑p, Vimentin (cow): S26‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S39-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S39‑p, Vimentin (mouse): S39‑p, Vimentin (rat): S39‑p, Vimentin (hamster): S39‑p, Vimentin (cow): S39‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S47-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S47‑p, Vimentin (mouse): S47‑p, Vimentin (rat): S47‑p, Vimentin (hamster): S46‑p, Vimentin (cow): T47‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S56-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S56‑p, Vimentin (mouse): S56‑p, Vimentin (rat): S56‑p, Vimentin (hamster): S55‑p, Vimentin (cow): S56‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S65-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S65‑p, Vimentin (mouse): S65‑p, Vimentin (rat): S65‑p, Vimentin (hamster): S64‑p, Vimentin (cow): S65‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S66-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S66‑p, Vimentin (mouse): S66‑p, Vimentin (rat): S66‑p, Vimentin (hamster): S65‑p, Vimentin (cow): S66‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S72-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S72‑p, Vimentin (mouse): S72‑p, Vimentin (rat): S72‑p, Vimentin (hamster): S71‑p, Vimentin (cow): S72‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S73-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S73‑p, Vimentin (mouse): S73‑p, Vimentin (rat): S73‑p, Vimentin (hamster): S72‑p, Vimentin (cow): G73‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S83-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S83‑p, Vimentin (mouse): S83‑p, Vimentin (rat): S83‑p, Vimentin (hamster): S82‑p, Vimentin (cow): S83‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .

S87-p - Vimentin (mouse)
Orthologous residues
Vimentin (human): S87‑p, Vimentin (mouse): S87‑p, Vimentin (rat): S87‑p, Vimentin (hamster): S86‑p, Vimentin (cow): S87‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  epithelial-lens [Vimentin (mouse), genetic knockin]
 Cellular systems studied:  tissue
 Species studied:  mouse
 Comments:  S/A mutant
Downstream Regulation
 Comments:  chromosomal instability, cytokinetic failure leading to binucleation and aneuploidy, fiber membranes were disorganized in the lenses of Vimentin SA/SA mutant .


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