|
Orthologous residues
|
|
ERK5 (human): S486‑p, ERK5 (mouse): S486‑p, ERK5 (rat): S486‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
immunoprecipitation, mutation of modification site, phospho-antibody
|
|
Relevant cell lines - cell types - tissues:
293T (epithelial)
|
|
Cellular systems studied:
cell lines
|
|
Species studied:
human
|
|
Downstream Regulation
|
|
Effect of modification (function):
enzymatic activity, inhibited, molecular association, regulation
|
|
Modification regulates interactions with:
|
|
Interacting molecule
|
Interacting domains
|
Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
14-3-3 beta (mouse)
|
|
Induces
|
|
|
|
|
