Curated Information

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Curated Information Page

PubMed Id: 7692235

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Fabian JR, Daar IO, Morrison DK (1993) Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol Cell Biol 13, 7170-9 7692235

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

Y340-p - c-Raf (human)

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Orthologous residues

c‑Raf (human): Y340‑p, c‑Raf (mouse): Y340‑p, c‑Raf (rat): Y340‑p, c‑Raf (chicken): Y340‑p

Characterization

Methods used to characterize site in vivo: mutation of modification site, phospho-antibody, phosphoamino acid analysis, phosphopeptide mapping

Relevant cell lines - cell types - tissues: 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout], SF9

Cellular systems studied: cell lines

Species studied: insect, mouse

Downstream Regulation

Effect of modification (function): enzymatic activity, induced

Y341-p - c-Raf (human)

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