Curated Information
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Curated Information Page
PubMed Id: 23857768 
Davydenko O, Schultz RM, Lampson MA (2013) Increased CDK1 activity determines the timing of kinetochore-microtubule attachments in meiosis I. J Cell Biol 202, 221-9 23857768
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S1120-p - separase (mouse)
Orthologous residues
separase (human): S1125‑p, separase (mouse): S1120‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  oocyte
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Effect of modification (process):  cytoskeletal reorganization
 Comments:  S1120 T1341 AA mutant -fewer cold-stable kinetochore-microtubule attachments and lacks tension

T1341-p - separase (mouse)
Orthologous residues
separase (human): T1346‑p, separase (mouse): T1341‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  oocyte
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Effect of modification (process):  cytoskeletal reorganization
 Comments:  S1120 T1341 AA mutant -fewer cold-stable kinetochore-microtubule attachments and lacks tension


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