Curated Information

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Curated Information Page

PubMed Id: 18494499

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Velusamy T, et al. (2008) Posttranscriptional regulation of urokinase receptor expression by heterogeneous nuclear ribonuclear protein C. Biochemistry 47, 6508-17 18494499

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

Y57-p - hnRNP C1/C2 (human)

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Orthologous residues

hnRNP C1/C2 (human): Y57‑p, hnRNP C1/C2 iso2 (human): Y57‑p, hnRNP C1/C2 iso4 (human): Y57‑p, hnRNP C1/C2 (mouse): Y57‑p, hnRNP C1/C2 iso2 (mouse): Y57‑p, hnRNP C1/C2 (rat): Y57‑p

Characterization

Methods used to characterize site in vivo: mutation of modification site, phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: BEAS-2B (epithelial)

Cellular systems studied: cell lines

Species studied: human

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
uPA				increase

Downstream Regulation

Effect of modification (function): molecular association, regulation

Modification regulates interactions with:

Interacting molecule	Interacting domains	Effect	Consequences (function)	Consequences (process)	Detection assays
RNA		Induces	protein stabilization		far-Western

Comments: Northwestern analysis, RNA stabilization

Y126-p - hnRNP C1/C2 (human)

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