Curated Information
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Curated Information Page
PubMed Id: 23300942 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Aizer A, Kafri P, Kalo A, Shav-Tal Y (2013) The P body protein Dcp1a is hyper-phosphorylated during mitosis. PLoS One 8, e49783 23300942
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S315-p - DCP1A (human)
Orthologous residues
DCP1A (human): S315‑p, DCP1A (mouse): S335‑p, DCP1A (rat): S335‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Disease tissue studied:  bone cancer
 Relevant cell lines - cell types - tissues:  U2OS (bone cell)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Comments:  hyperphosphorylated during mitosis

S319-p - DCP1A (human)
Orthologous residues
DCP1A (human): S319‑p, DCP1A (mouse): S339‑p, DCP1A (rat): S339‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Disease tissue studied:  bone cancer
 Relevant cell lines - cell types - tissues:  U2OS (bone cell)
 Cellular systems studied:  cell lines
 Species studied:  human

S522-p - DCP1A (human)
Orthologous residues
DCP1A (human): S522‑p, DCP1A (mouse): S542‑p, DCP1A (rat): S542‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Disease tissue studied:  bone cancer
 Relevant cell lines - cell types - tissues:  U2OS (bone cell)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Comments:  affect DCP1A association/dissociation dynamics in processing bodies (PBs)

S523-p - DCP1A (human)
Orthologous residues
DCP1A (human): S523‑p, DCP1A (mouse): S543‑p, DCP1A (rat): C543‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Disease tissue studied:  bone cancer
 Relevant cell lines - cell types - tissues:  U2OS (bone cell)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Comments:  affect DCP1A association/dissociation dynamics in processing bodies (PBs)


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