|
Orthologous residues
|
|
DARPP‑32 (human): T34‑p, DARPP‑32 (mouse): T34‑p, DARPP‑32 (rat): T34‑p, DARPP‑32 (cow): T34‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
phospho-antibody, western blotting
|
|
Disease tissue studied:
Huntington's disease
|
|
Relevant cell lines - cell types - tissues:
'neuron, cerebral cortical'-brain
|
|
Cellular systems studied:
primary cells
|
|
Species studied:
mouse
|
|
Upstream Regulation
|
|
Treatments, proteins and their effect on site modification:
|
|
Treatments
|
Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
forskolin
|
|
|
|
increase
|
|
|
SKF81297
|
|
|
|
increase
|
|
|
|
Associated Diseases
|
|
Diseases:
|
Alterations:
|
Comments:
|
|
Huntington's disease
|
decreased
|
decreased in Huntington's disease mouse model
|
|
