Curated Information
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Curated Information Page
PubMed Id: 10829080 
Bibb JA, et al. (2000) Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice. Proc Natl Acad Sci U S A 97, 6809-14 10829080
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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T34-p - DARPP-32 (mouse)
Orthologous residues
DARPP‑32 (human): T34‑p, DARPP‑32 (mouse): T34‑p, DARPP‑32 (rat): T34‑p, DARPP‑32 (cow): T34‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Disease tissue studied:  Huntington's disease
 Relevant cell lines - cell types - tissues:  'neuron, cortical'-brain
 Cellular systems studied:  primary cells
 Species studied:  mouse
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
forskolin increase
SKF81297 increase
Associated Diseases
Diseases: Alterations: Comments:
Huntington's disease decreased decreased in Huntington's disease mouse model


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