Curated Information

Javascript is not enabled on this browser. This site will not work properly without Javascript.

Home

Curated Information Page

PubMed Id: 21448926

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Ramakrishnan R, Rice AP (2012) Cdk9 T-loop phosphorylation is regulated by the calcium signaling pathway. J Cell Physiol 227, 609-17 21448926

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

T160-p - CDK2 (human)

▲

Orthologous residues

CDK2 (human): T160‑p, CDK2 (mouse): T160‑p, CDK2 (rat): T160‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: mononuclear-blood

Cellular systems studied: primary cells

Species studied: human

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
KN-93				decrease
KN-92				no change compared to control
W-7				decrease

T186-p - CDK9 (human)

▲

Orthologous residues

CDK9 (human): T186‑p, CDK9 iso2 (human): T303‑p, CDK9 (mouse): T186‑p, CDK9 (rat): T186‑p