Curated Information

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Curated Information Page

PubMed Id: 17254973

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Basak S, et al. (2007) A fourth IkappaB protein within the NF-kappaB signaling module. Cell 128, 369-81 17254973

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

S32-p - IkB-alpha (mouse)

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Orthologous residues

IkB‑alpha (human): S32‑p, IkB‑alpha (mouse): S32‑p, IkB‑alpha (rat): S32‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: MEF (fibroblast)

Cellular systems studied: cell lines

Species studied: mouse

Enzymes shown to modify site in vitro:

Type	Enzyme
KINASE	IKKA (mouse)

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
TNF				increase
anti-LT(beta)R				no change compared to control

S36-p - IkB-alpha (mouse)

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