Curated Information
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Curated Information Page
PubMed Id: 10958691 
Garber ME, et al. (2000) CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA. Mol Cell Biol 20, 6958-69 10958691
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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S347-p - CDK9 (human)
Orthologous residues
CDK9 (human): S347‑p, CDK9 iso2 (human): S464‑p, CDK9 (mouse): S347‑p, CDK9 (rat): S347‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK9 (human)
 Comments:  autophosphorylation
Downstream Regulation
 Effect of modification (function):  molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
RNA Induces EMSA
 Comments:  HIV-1 TAR RNA

S353-p - CDK9 (human)
Orthologous residues
CDK9 (human): S353‑p, CDK9 iso2 (human): S470‑p, CDK9 (mouse): S353‑p, CDK9 (rat): S353‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK9 (human)
 Comments:  autophosphorylation

T354-p - CDK9 (human)
Orthologous residues
CDK9 (human): T354‑p, CDK9 iso2 (human): T471‑p, CDK9 (mouse): T354‑p, CDK9 (rat): T354‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK9 (human)
 Comments:  autophosphorylation

S1616-p - POLR2A (human)
Orthologous residues
POLR2A (human): S1616‑p, POLR2A var1 (human): S1616‑p, POLR2A (mouse): S1616‑p, POLR2A (rat): S1616‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK9 (human)

S1619-p - POLR2A (human)
Orthologous residues
POLR2A (human): S1619‑p, POLR2A var1 (human): S1619‑p, POLR2A (mouse): S1619‑p, POLR2A (rat): S1619‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK9 (human)


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