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Orthologous residues
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FOXO3A (human): S626‑p, FOXO3A (mouse): S625‑p, FOXO3A (rat): S625‑p
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Characterization
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|
Methods used to characterize site in vivo:
mutation of modification site
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Disease tissue studied:
colorectal cancer, colorectal carcinoma
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|
Relevant cell lines - cell types - tissues:
293T (epithelial), HCT116 (intestinal), MEF (fibroblast)
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Cellular systems studied:
cell lines
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|
Species studied:
human, mouse
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Effect of modification (process):
transcription, induced
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Modification regulates interactions with:
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Interacting molecule
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Interacting domains
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Effect
|
Consequences (function)
|
Consequences (process)
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Detection assays
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|
CBP (human)
|
KIX, zf-TAZ
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Induces
|
|
|
NMR spectroscopy
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|
