Curated Information
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Curated Information Page
PubMed Id: 22119528 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
An SW, et al. (2011) WNK1 promotes PIPâ‚‚ synthesis to coordinate growth factor and GPCR-Gq signaling. Curr Biol 21, 1979-87 22119528
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T60-p - WNK1 (human) ▲
Orthologous residues
WNK1 (human): T60‑p, WNK1 iso4 (human): T60‑p, WNK1 (mouse): T58‑p, WNK1 iso3 (mouse): T58‑p, WNK1 iso8 (mouse): ‑, WNK1 (rat): T58‑p
Characterization
 Methods used to characterize site in vivo:  mutation of modification site
 Relevant cell lines - cell types - tissues:  293 (epithelial), HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Comments:  regulates IGF induced channel current


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