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Orthologous residues
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MYH9 (human): S1943‑p, MYH9 (mouse): S1943‑p, MYH9 (rat): S1944‑p
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Characterization
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Methods used to characterize site in vivo:
mutation of modification site, phospho-antibody, western blotting
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Relevant cell lines - cell types - tissues:
natural killer cell-blood, YTS
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Cellular systems studied:
primary cells
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Species studied:
human
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Comments:
interacts with lytic granules, colocalized with perforin, and required for NK-cell cytotoxicity
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