Curated Information
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Curated Information Page
PubMed Id: 11581251 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Greenberg AS, et al. (2001) Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway. J Biol Chem 276, 45456-61 11581251
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S900-p - HSL (rat)
Orthologous residues
HSL (human): T891‑p, HSL iso2 (human): T590‑p, HSL (mouse): S904‑p, HSL (rat): S900‑p, HSL iso2 (rat): S600‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout]
 Cellular systems studied:  cell lines
 Species studied:  mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE ERK1 (rat)
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced


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