|
Orthologous residues
|
|
MOB1A (human): T74‑p, MOB1A (mouse): T74‑p, MOB1A (rat): T74‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling, immunoprecipitation, mutation of modification site
|
|
Relevant cell lines - cell types - tissues:
293FT
|
|
Cellular systems studied:
cell lines
|
|
Species studied:
human
|
|
Enzymes shown to modify site in vitro:
|
|
|
|
Downstream Regulation
|
|
Effect of modification (function):
molecular association, regulation
|
|
Modification regulates interactions with:
|
|
Interacting molecule
|
Interacting domains
|
Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
MST2 (human)
|
|
Induces
|
|
|
co-immunoprecipitation
|
|
NDR1 (human)
|
|
Induces
|
enzymatic activity, induced
|
|
co-immunoprecipitation
|
|
|
Comments:
a tripartite complex
|
