|
Orthologous residues
|
|
CDH5 (human): S665‑p, CDH5 (mouse): S665‑p, CDH5 (rat): S657‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
phospho-antibody
|
|
Relevant cell lines - cell types - tissues:
skin, SVEC (endothelial)
|
|
Cellular systems studied:
cell lines, tissue
|
|
Species studied:
mouse
|
|
Upstream Regulation
|
|
Treatments, proteins and their effect on site modification:
|
|
Treatments
|
Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
angiopoietin-1
|
|
|
|
decrease
|
|
|
VEGF
|
|
|
|
increase
|
|
|
angiopoietin-1
|
VEGF
|
|
|
inhibit treatment-induced increase
|
|
|
|
Downstream Regulation
|
|
Effect of modification (function):
intracellular localization
|
