Curated Information
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Curated Information Page
PubMed Id: 11802161 
Okumura E, et al. (2002) Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition. Nat Cell Biol 4, 111-6 11802161
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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S75-p - Myt1 (starfish)
Orthologous residues
Myt1 (human): S83‑p, Myt1 (mouse): S74‑p, Myt1 (starfish): S75‑p
Characterization
 Methods used to characterize site in vivo [32P] bio-synthetic labeling, mutation of modification site, phospho-antibody, phosphopeptide mapping
 Relevant cell lines - cell types - tissues:  oocyte [CPEB (mouse)]
 Cellular systems studied:  primary cells
 Species studied:  starfish
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE Akt1 (human)
Upstream Regulation
 Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE Akt1 (human) transfection of constitutively active enzyme, transfection of inactive enzyme
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
1-methyladenine increase
Downstream Regulation
 Effect of modification (function):  activity, inhibited
 Effect of modification (process):  cell cycle regulation


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