|
Orthologous residues
|
|
CAMK2A (human): T286‑p, CAMK2A iso2 (human): T286‑p, CAMK2A (mouse): T286‑p, CAMK2A iso2 (mouse): ‑, CAMK2A (rat): T286‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
phospho-antibody
|
|
Relevant cell lines - cell types - tissues:
'brain, hippocampus'
|
|
Cellular systems studied:
tissue
|
|
Species studied:
mouse
|
|
Upstream Regulation
|
|
Potential in vivo enzymes for site:
|
|
Type
|
Enzyme
|
Evidence
|
Notes
|
|
KINASE
|
CAMK2A (mouse)
|
antisense inhibition of upstream enzyme, pharmacological activator of upstream enzyme
|
|
|
|
Treatments, proteins and their effect on site modification:
|
|
Treatments
|
Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
Ca(2+)
|
|
|
|
increase
|
|
|
electrical stimulation
|
|
|
|
increase
|
|
|
forskolin
|
|
|
|
increase
|
|
|
calyculin A
|
|
|
|
increase
|
|
|
APV
|
|
|
|
no change compared to control
|
|
|
isoproterenol
|
|
|
|
no change compared to control
|
|
|
