Curated Information
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Curated Information Page
PubMed Id: 22139840 
Barrientos GC, et al. (2012) Gene Dose Influences Cellular and Calcium Channel Dysregulation in Heterozygous and Homozygous T4826I-RYR1 Malignant Hyperthermia-susceptible Muscle. J Biol Chem 287, 2863-76 22139840
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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S2844-p - RYR1 (mouse)
Orthologous residues
RYR1 (human): S2843‑p, RYR1 (mouse): S2844‑p, RYR1 (rat): S2840‑p, RYR1 (rabbit): S2843‑p
 Methods used to characterize site in vivo phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  'muscle, skeletal'
 Cellular systems studied:  tissue
 Species studied:  mouse
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
RYR1 (mouse) no change compared to control RYR1 T4826I knock-in mice

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