|
Orthologous residues
|
|
APS (human): Y629‑p, APS (mouse): Y618‑p, APS (rat): Y618‑p
|
|
Characterization
|
|
Methods used to characterize site in vivo:
immunoprecipitation, mutation of modification site, phospho-antibody, western blotting
|
|
Relevant cell lines - cell types - tissues:
CHO (fibroblast) [APS (mouse)], CHO (fibroblast) [InsR (mouse)]
|
|
Cellular systems studied:
cell lines
|
|
Species studied:
hamster
|
|
Upstream Regulation
|
|
Potential in vivo enzymes for site:
|
|
Type
|
Enzyme
|
Evidence
|
Notes
|
|
KINASE
|
InsR (mouse)
|
transfection of wild-type enzyme
|
|
|
|
Treatments, proteins and their effect on site modification:
|
|
Treatments
|
Referenced Treatments
|
Manipulated Protein
|
Referenced Protein
|
Effect
|
Notes
|
|
insulin
|
|
InsR (mouse)
|
|
increase
|
|
|
